used to treat all fungal skin infections such as infection of the vulva and also used with other medicines to treat infection of the vagina. It is also used to prevent reinfection by applying on the penis of the sexual partner. Locasten solution can also be used to treat fungal infections of the middle ear and outer ear. This medicine works by blocking the synthesis of a substance in the cell membranes of?fungi. It may lead to functional and structural dysfunction of fungi.