ZGTS (Cosmo JNS) Dermarolling remoulds the skin by creating thousands of microscopic channels through the skin, increasing the formation of new tissue by activating the body?s wound healing cascade (haemostasis-inflammation-proliferation-tissue remodelling). The micro-channelling causes the release of growth factors that promote scar-less healing and the deposition of normal woven collagen rather than scar collagen. The fibroblasts are responsible for collagen production. The exact mechanism how this happens is complex and not yet completely understood. New collagen and elastin forms. In one study, twenty blinded biopsies taken from 10 different patients from various parts of their body demonstrated an average increase in new fibres of 206%, in one biopsy a 1000% increase was recorded.